Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer’s disease. Nat Commun. 2023 Mar 24;14(1):1631.
Discovery of a dual-action small molecule that improves neuropathological features of Alzheimer's disease mice. Proc Natl Acad Sci U S A. 2022 Jan 18
N-AS-triggered SPMs are direct regulators of microglia in a model of Alzheimer’s disease. Nat Commun 2020 May 12.
N,N'-Diacetyl-p-phenylenediamine restores microglial phagocytosis and improves cognitive defects in Alzheimer's disease transgenic mice. PNAS 2019 Nov 4.
Characterization of the Subventricular-Thalamo-Cortical Circuit in the NP-C Mouse Brain, and New Insights Regarding Treatment. Mol Ther. 2019 Aug 7;27(8):1507-1526.
Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM. Neuron. 2018 Oct 10;100(1):167-182.
Neuronal Sphk1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease Nat Commun. 2018 Apr 16:9(1);1479.
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